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Services
We offer the following Services: | Production of Mammalian Cell Culture: | • Recombinant Proteins
• Monoclonal Antibodies
• Viruses and Viral vectors
• Stem Cells
| | | Cytotoxicity & Cytocompatibility Assays : | • Caco-2 permeability assay
• LDH Release
• Apoptosis detection
• Mitochondrial activity assay
| | | Molecular Biology: | • Cloning
• SDS-PAGE
• DNA gel electrophoresis | | | Specific Cell Population Isolation | • Master cell bank production
• Master cell bank Storage
• Mycoplasma detection
| | | Purification & Purification Optimisation: | • Microfiltration
• Ultrafiltration
• HPLC and FPLC
- Affinity, Ion exchange, Reverse Phase and Size exclusion chromatography
| | | Scale-Up Services : | • Fully instrumented bioreactors with production capacity from 10 to more than 100 litres per week.
• Scale up of the entire bioprocess from the initial lab scale culture to the final steps of purification, in a cGMP compatible environment.
• All of the installations are biosafety level 2 approved by Health Canada
| | | Production Process Development : | • Serum free medium development using statistical design of experiment
• Yield optimisation regarding the physical conditions, process mode and media formulation
| | | Other available services : | • Lyophilisation
• Sonication
• ELISA Assay
• Data handling and multivariate analysis
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